From Indianapolis using I-70 

Take I-70 east from Indianapolis and exit south at Exit 137 onto SR 1. Follow the signs on the south side of Connersville to SR 121. Head south on SR 121 for approximately 3.5 miles to CR 350 S, which will be on your right just after a bridge. Turn right (west) onto CR 350 S. Drive approximately 3 miles, where you will come to a 90° turn. The gravel road directly in front of you is the beautiful Sanctuary entrance.

From Indianapolis using SR 52 and SR 44

Take Highway 52 from Indianapolis to Rushville, where you will want to catch SR 44. Drive east on SR 44 until to CR 525 W in Fayette County, which is approximately 3.5 miles from the Fayette/Rush County line. Turn right(south) on CR 525 W for drive for 0.7 mile. Turn left (east) onto CR 150 S and drive 0.7 mile. At the next intersection, turn right (south) on the winding Bird Sanctuary Road. In 1.2 miles you will come to a "T" intersection. Turn right into the beautiful Sanctuary entrance road.

From Cincinnati 

Exit I-74 in Indiana at Exit 169 (Highway 52). Drive north on Highway 52 through Brookville and Metamora to SR 121. Turn right (north) onto SR 121 and drive approximately 12 miles to CR 350 S (look for the sign indicating the turn off for Mary Gray Bird Sanctuary). Drive approximately 3 miles. The gravel road directly in front of you is the beautiful Sanctuary entrance.